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Monofilament testing quickly identifies patients with advanced largefiber loss and a sevenfold higher risk of foot ulceration, but its low sensitivity means early neuropathy is often missed

Decreased energy production in the brain leads to decreased neurogenesis in the hippocampus and researchers hypothesize that this is the cause of long-term depression

While total metabolic rate changes are typically modest, the combination of age-related muscle loss, reduced physical activity, and hormonal shifts can make weight management more challenging during this life stage

But heres the exciting part: recent studies suggest that metformins benefits go way beyond blood sugar control